验证数据展示
产品信息
98018-1-PBS targets TLR4/CD284 in FC applications and shows reactivity with mouse samples.
Tested Applications | FC Application Description |
Tested Reactivity | mouse |
Immunogen | TLR4/CD284 fusion protein Ag32998 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | toll-like receptor 4 |
Synonyms | Tlr4, CD284, toll like receptor 4, 230463C7 |
Calculated Molecular Weight | 96 kDa |
GenBank Accession Number | NM_021297 |
Gene Symbol | Tlr4 |
Gene ID (NCBI) | 21898 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q9QUK6 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.