验证数据展示
产品信息
98018-1-PBS targets TLR4/CD284 in FC applications and shows reactivity with mouse samples.
经测试应用 | FC Application Description |
经测试反应性 | mouse |
免疫原 | TLR4/CD284 fusion protein Ag32998 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | toll-like receptor 4 |
别名 | Tlr4, CD284, toll like receptor 4, 230463C7 |
计算分子量 | 96 kDa |
GenBank蛋白编号 | NM_021297 |
基因名称 | Tlr4 |
Gene ID (NCBI) | 21898 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | Q9QUK6 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.