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TP63 Monoclonal antibody, PBS Only

TP63 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

4D6G12

Cat no : 60332-2-PBS

Print datasheet

Synonyms

TP63

验证数据展示

  • WB analysis of HaCaT using 60332-2-Ig (same clone as 60332-2-PBS)

    WB analysis of HaCaT using 60332-2-Ig (same clone as 60332-2-PBS)

    HaCaT cells were subjected to SDS PAGE followed by western blot with 60332-2-Ig (TP63 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

  • IHC staining of rat skin using 60332-2-Ig (same clone as 60332-2-PBS)

    IHC staining of rat skin using 60332-2-Ig (same clone as 60332-2-PBS)

    Immunohistochemical analysis of paraffin-embedded rat skin tissue slide using 60332-2-Ig (TP63 antibody) at dilution of 1:4000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TP63 antibody included
  • WB analysis of A431 using 60332-2-Ig (same clone as 60332-2-PBS)

    WB analysis of A431 using 60332-2-Ig (same clone as 60332-2-PBS)

    A431 cells were subjected to SDS PAGE followed by western blot with 60332-2-Ig (TP63 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

  • IHC staining of mouse skin using 60332-2-Ig (same clone as 60332-2-PBS)

    IHC staining of mouse skin using 60332-2-Ig (same clone as 60332-2-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 60332-2-Ig (TP63 antibody) at dilution of 1:4000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TP63 antibody included
  • WB analysis of U-937 using 60332-2-Ig (same clone as 60332-2-PBS)

    WB analysis of U-937 using 60332-2-Ig (same clone as 60332-2-PBS)

    U-937 cells were subjected to SDS PAGE followed by western blot with 60332-2-Ig (TP63 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 60332-2-Ig (same clone as 60332-2-PBS)

    IHC staining of human prostate cancer using 60332-2-Ig (same clone as 60332-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 60332-2-Ig (TP63 antibody) at dilution of 1:4000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TP63 antibody included
Planning an IHC experiment? We recommend our IHCeasy TP63 Ready-To-Use IHC Kit. TP63 primary antibody included.

产品信息

60332-2-PBS targets TP63 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen TP63 fusion protein Ag2791 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name tumor protein p63
Synonyms TP63
Calculated Molecular Weight 680 aa, 77 kDa
Observed Molecular Weight70 kDa
GenBank Accession NumberBC039815
Gene Symbol TP63
Gene ID (NCBI) 8626
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9H3D4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40), 50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.