TP63 Monoclonal antibody, PBS Only

TP63 Monoclonal Antibody for WB,Indirect ELISA,IHC

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

WB,Indirect ELISA,IHC

Conjugate

Unconjugated

CloneNo.

4D6G12

Cat No : 60332-2-PBS

Print datasheet

Synonyms

TP63



Planning an IHC experiment? We recommend our IHCeasy TP63 Ready-To-Use IHC Kit. TP63 primary antibody included.

产品信息

60332-2-PBS targets TP63 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB,Indirect ELISA,IHC Application Description
Tested Reactivity human
Immunogen TP63 fusion protein Ag2791 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name tumor protein p63
Synonyms TP63
Calculated Molecular Weight 680 aa, 77 kDa
Observed Molecular Weight70 kDa
GenBank Accession NumberBC039815
Gene Symbol TP63
Gene ID (NCBI) 8626
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9H3D4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40), 50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.