验证数据展示
产品信息
60332-2-PBS targets p63 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | p63 fusion protein Ag2791 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | tumor protein p63 |
别名 | TP63, tumor protein p63, Tumor protein 63, Transformation-related protein 63, TP 63 |
计算分子量 | 680 aa, 77 kDa |
观测分子量 | 70 kDa |
GenBank蛋白编号 | BC039815 |
基因名称 | TP63 |
Gene ID (NCBI) | 8626 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q9H3D4 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40), 50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.