CoraLite® Plus 488-conjugated TRIM2 Monoclonal antibody
TRIM2 Monoclonal Antibody for IF-P
Host / Isotype
Mouse / IgG1
Reactivity
Human, Mouse, Rat, Pig
Applications
IF-P
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1H9C2
验证数据展示
经过测试的应用
| Positive IF-P detected in | mouse brain tissue |
For other applications, we recommend the unconjugated version of this antibody, 67342-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-67342 targets TRIM2 in IF-P applications and shows reactivity with Human, Mouse, Rat, Pig samples.
| Tested Applications | IF-P Application Description |
| Tested Reactivity | Human, Mouse, Rat, Pig |
| Immunogen | TRIM2 fusion protein Ag14637 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | tripartite motif-containing 2 |
| Synonyms | KIAA0517, RING finger protein 86, RNF86, TRIM2, tripartite motif containing 2 |
| Calculated Molecular Weight | 744 aa, 82 kDa |
| Observed Molecular Weight | 70-85 kDa |
| GenBank Accession Number | BC011052 |
| Gene Symbol | TRIM2 |
| Gene ID (NCBI) | 23321 |
| RRID | AB_2919456 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | Q9C040 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Tripartite motif-containing 2(TRIM2) is an E3 ubiquitin ligase which directs proteasome-mediated degradation of target proteins by the ubiquitination of NEFL and phosphorylation of BCL2L11. This protein contains an N-terminal RING domain, followed by a B-box-2 domain, a coiled-coil region, and 6 C-terminal NHL repeats. TRIM2 involves in the apoptotic response to ischemia via directing degradation of BIM protein, thus has a role in neuroprotection.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 TRIM2 antibody CL488-67342 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |