CoraLite® Plus 488-conjugated Thyroglobulin Monoclonal antibody

Thyroglobulin Monoclonal Antibody for IF-P
Cat No. CL488-60272

产品说明书

CloneNo. 4D3C5

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

IF-P

TG, 4D3C5

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -


经过测试的应用

Positive IF-P detected inhuman thyroid cancer tissue
For other applications, we recommend the unconjugated version of this antibody, 60272-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-60272 targets Thyroglobulin in IF-P applications and shows reactivity with human samples.

经测试应用 IF-P Application Description
经测试反应性 human
免疫原 Thyroglobulin fusion protein Ag18070 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 thyroglobulin
别名 TG, 4D3C5
计算分子量 2768 aa, 305 kDa
GenBank蛋白编号BC140933
基因名称 Thyroglobulin
Gene ID (NCBI) 7038
RRIDAB_2919242
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP01266
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 Thyroglobulin antibody CL488-60272Download protocol
Standard Protocols
Click here to view our Standard Protocols
Loading...