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Host
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Species Reactivity
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Species Reactivity
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验证数据展示

  • FC experiment of mouse splenocytes using 98022-1-RR (same clone as 98022-1-PBS)

    FC experiment of mouse splenocytes using 98022-1-RR (same clone as 98022-1-PBS)

    1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse TREM-1/CD354 Rabbit Recombinant Antibody (98022-1-RR, Clone:240219H1) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse Ly-6G/Ly-6C (Gr-1) (RB6-8C5) (APC-65140, Clone: RB6-8C5). Cells were not fixed. This data was developed using the same antibody clone with 98022-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98022-1-RR

    Affinity and Kinetic Characterization of 98022-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98022-1-RR against Mouse CD354/TREM-1 were performed. The affinity constant is 91.8 nM.

Anti-Mouse TREM-1/CD354 Rabbit Recombinant Antibody, PBS Only

TREM-1/CD354 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98022-1-PBS

产品说明书

CloneNo. 240219H1

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

Trem1, TREM-1, TREM 1, CD354, 240219H1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98022-1-PBS targets TREM-1/CD354 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 triggering receptor expressed on myeloid cells 1
别名 Trem1, TREM-1, TREM 1, CD354, 240219H1
计算分子量25 kDa
GenBank蛋白编号NM_021406.5
基因名称 Trem1
Gene ID (NCBI) 58217
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ9JKE2
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Triggering receptor expressed on myeloid cells 1 (TREM-1, also known as CD354) is a member of the immunoglobulin superfamily, which is expressed on neutrophils and monocytes. TREM1 plays a role in the innate immune system. TREM1 amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers.