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UPF1 Recombinant antibody, PBS Only

UPF1 Recombinant Antibody for WB,Indirect ELISA,IF

Host / Isotype

Rabbit / IgG

Reactivity

Human, rat

Applications

WB,Indirect ELISA,IF

Conjugate

Unconjugated

CloneNo.

3O15

Cat No : 82791-1-PBS

Print datasheet

Synonyms

ATP dependent helicase RENT1, FLJ43809, FLJ46894, HUPF1, KIAA0221, NORF1, pNORF1, RENT1, UPF1

验证数据展示

  • WB analysis using 82791-1-RR (same clone as 82791-1-PBS)

    WB analysis using 82791-1-RR (same clone as 82791-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82791-1-RR (UPF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82791-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 82791-1-RR (same clone as 82791-1-PBS)

    IF Staining of HepG2 using 82791-1-RR (same clone as 82791-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using UPF1 antibody (82791-1-RR, Clone: 3O15 ) at dilution of 1:370 and Multi-rAb CoraLite ® Plus 594-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR004). This data was developed using the same antibody clone with 82791-1-PBS in a different storage buffer formulation.

产品信息

82791-1-PBS targets UPF1 in WB, IF, Indirect ELISA applications and shows reactivity with Human, rat samples.

Tested Applications WB,Indirect ELISA,IF Application Description
Tested Reactivity Human, rat
Immunogen UPF1 fusion protein Ag29057 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name UPF1 regulator of nonsense transcripts homolog (yeast)
Synonyms ATP dependent helicase RENT1, FLJ43809, FLJ46894, HUPF1, KIAA0221, NORF1, pNORF1, RENT1, UPF1
Calculated Molecular Weight123 kDa
Observed Molecular Weight 123-130 kDa
GenBank Accession NumberBC039817
Gene Symbol UPF1
Gene ID (NCBI) 5976
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ92900
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

Up-Frameshift Suppressor 1 Homolog (UPF1) is the central factor in nonsense-mediated mRNA decay (NMD) and is also directly involved in telomere homeostasis, DNA replication, histone mRNA degradation and staufen-mediated mRNA decay (PMID: 29382845). It is a potential modulator of MALAT1 and that UPF1/MALAT1 pathway could be a therapeutic target for gastric cancer (PMID: 28942451). The molecular mass of UPF1 is 123-130 kDa.