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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis of human urine using 29975-1-AP (same clone as 29975-1-PBS)

    WB analysis of human urine using 29975-1-AP (same clone as 29975-1-PBS)

    human urine sample were subjected to SDS PAGE followed by western blot with 29975-1-AP (Uromodulin antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29975-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 29975-1-AP (same clone as 29975-1-PBS)

    IHC staining of human kidney using 29975-1-AP (same clone as 29975-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 29975-1-AP (Uromodulin antibody) at dilution of 1:10000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29975-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 29975-1-AP (same clone as 29975-1-PBS)

    IHC staining of human kidney using 29975-1-AP (same clone as 29975-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 29975-1-AP (Uromodulin antibody) at dilution of 1:10000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29975-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse kidney using 29975-1-AP (same clone as 29975-1-PBS)

    IF Staining of mouse kidney using 29975-1-AP (same clone as 29975-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse kidney tissue using Uromodulin antibody (29975-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 29975-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse kidney using 29975-1-AP (same clone as 29975-1-PBS)

    IF Staining of mouse kidney using 29975-1-AP (same clone as 29975-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse kidney tissue using Uromodulin antibody (29975-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 29975-1-PBS in a different storage buffer formulation.

Uromodulin Polyclonal antibody, PBS Only

Uromodulin Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 29975-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IF-P, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

29975-1-PBS targets Uromodulin in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 Uromodulin fusion protein Ag32343 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 uromodulin
别名
计算分子量 640 aa, 70 kDa
观测分子量80-90 kDa
GenBank蛋白编号BC035975
基因名称 Uromodulin
Gene ID (NCBI) 7369
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP07911
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Uromodulin, also known as THP (Tamm-Horsfall glycoprotein), is the most abundant protein excreted in the urine under physiological conditions. Uromodulin is synthesized by the kidney and localizes in cells lining the ascending limb of Henle and distal convoluted tubule. Uromodulin has been linked to water/electrolyte balance and to kidney innate immunity. Also, studies in knockout mice demonstrated that it has a protective role against urinary tract infections and renal stone formation. Mutations in the gene encoding uromodulin lead to rare autosomal dominant diseases, collectively referred to as uromodulin-associated kidney diseases. (PMID: 21654721)