WAPL Recombinant antibody, PBS Only

WAPL Uni-rAbTM Recombinant Antibody for WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Cat No. 84877-5-PBS

Print datasheet

CloneNo. 242443C1

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF/ICC, FC (Intra), Indirect ELISA

WAPL/FOE, FOE, 242443C1, WAPL cohesin release factor, WAPAL

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

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Planning an IHC experiment? We recommend our IHCeasy WAPL Ready-To-Use IHC Kit. WAPL primary antibody included.

产品信息

84877-5-PBS targets WAPL in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, IF/ICC, FC (Intra), Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen WAPL fusion protein Ag9585 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name wings apart-like homolog (Drosophila)
Synonyms WAPL/FOE, FOE, 242443C1, WAPL cohesin release factor, WAPAL
Calculated Molecular Weight 142 kDa
Observed Molecular Weight 160-180 kDa
GenBank Accession NumberBC017393
Gene Symbol WAPL
Gene ID (NCBI) 23063
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ7Z5K2
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The wings apart-like (WAPL, or WAPAL) protein was originally identified as a gene product that potentially regulates heterochromatin organization in Drosophila melanogaster. Human WAPL is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase. Overexpression of WAPL disturbs mitosis and cytokinesis, and contributes to tumor progression by induction of chromosomal instability. WAPAL has a predicted molecular weight of 140 kDa, however, as a result of its extensive phosphorylation it separates on a SDS gel as a band of approximately 160-180 kDa.

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