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WFS1 Monoclonal antibody, PBS Only

WFS1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, pig

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

4C2B5

Cat no : 67291-1-PBS

Print datasheet

Synonyms

FLJ51211, WFRS, WFS, WFS1, Wolfram syndrome 1 (wolframin), WOLFRAMIN

验证数据展示

  • WB analysis using 67291-1-Ig (same clone as 67291-1-PBS)

    WB analysis using 67291-1-Ig (same clone as 67291-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67291-1-Ig (WFS1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67291-1-PBS in a different storage buffer formulation.

  • WB analysis of A172 using 67291-1-Ig (same clone as 67291-1-PBS)

    WB analysis of A172 using 67291-1-Ig (same clone as 67291-1-PBS)

    A172 cells were subjected to SDS PAGE followed by western blot with 67291-1-Ig (WFS1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67291-1-PBS in a different storage buffer formulation.

  • WB analysis using 67291-1-Ig (same clone as 67291-1-PBS)

    WB analysis using 67291-1-Ig (same clone as 67291-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67291-1-Ig (WFS1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67291-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy WFS1 Ready-To-Use IHC Kit. WFS1 primary antibody included.

产品信息

67291-1-PBS targets WFS1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat, pig
Immunogen WFS1 fusion protein Ag25735 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name Wolfram syndrome 1 (wolframin)
Synonyms FLJ51211, WFRS, WFS, WFS1, Wolfram syndrome 1 (wolframin), WOLFRAMIN
Calculated Molecular Weight 890 aa, 100 kDa
Observed Molecular Weight 100 kDa
GenBank Accession NumberBC030130
Gene Symbol WFS1
Gene ID (NCBI) 7466
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDO76024
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Wolfram syndrome protein (WFS1), also called wolframin, is a transmembrane protein, which is located primarily in the endoplasmic reticulum and its expression is induced in response to ER stress, partially through transcriptional activation. ER localization suggests that WFS1 protein has physiological functions in membrane trafficking, secretion, processing and/or regulation of ER calcium homeostasis. It is ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations of the WFS1 gene are responsible for two hereditary diseases, autosomal recessive Wolfram syndrome and autosomal dominant low frequency sensorineural hearing loss.