验证数据展示
产品信息
67804-1-PBS targets WWP1 in WB, Indirect ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human |
免疫原 | WWP1 fusion protein Ag30171 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | WW domain containing E3 ubiquitin protein ligase 1 |
别名 | AIP5, DKFZp434D2111, hSDRP1, Tiul1, WW domain containing protein 1, WWP1 |
计算分子量 | 922 aa, 105 kDa |
观测分子量 | 95-105 kDa |
GenBank蛋白编号 | BC036065 |
基因名称 | WWP1 |
Gene ID (NCBI) | 11059 |
RRID | AB_2918567 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q9H0M0 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) is a multifunction protein containing an N-terminal C2 domain, four tandem WW domains for substrate binding, and a C-terminal catalytic HECT domain for ubiquitin transferring. It is also named as AIP5, Tiul1. WWP1 regulates a variety of cellular biological processes including protein trafficking and degradation, signaling, transcription, and viral budding. WWP1 has been implicated in several diseases, such as cancers, infectious diseases, neurological diseases, and aging(PMID:22051607). It has 6 isoforms produced by alternative splicing.