• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 67274-1-Ig (same clone as 67274-1-PBS)

    WB analysis using 67274-1-Ig (same clone as 67274-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67274-1-Ig (WWP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67274-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 67274-1-Ig (same clone as 67274-1-PBS)

    IHC staining of human pancreas cancer using 67274-1-Ig (same clone as 67274-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 67274-1-Ig (WWP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67274-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 67274-1-Ig (same clone as 67274-1-PBS)

    IHC staining of human pancreas cancer using 67274-1-Ig (same clone as 67274-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 67274-1-Ig (WWP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67274-1-PBS in a different storage buffer formulation.

WWP2 Monoclonal antibody, PBS Only

WWP2 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 67274-1-PBS

产品说明书

CloneNo. 2C9B4

宿主/亚型

Mouse / IgG1

种属反应性

Human, Rat

应用

WB, IHC, Indirect ELISA

别名

AIP2, WW domain containing protein 2, WWP2, WWp2 like

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

67274-1-PBS targets WWP2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 Human, Rat
免疫原 WWP2 fusion protein Ag2835 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 WW domain containing E3 ubiquitin protein ligase 2
别名 AIP2, WW domain containing protein 2, WWP2, WWp2 like
计算分子量 870 aa, 99 kDa
观测分子量 100-115 kDa
GenBank蛋白编号BC013645
基因名称 WWP2
Gene ID (NCBI) 11060
RRIDAB_2882543
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDO00308
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

WWP2 (WW domain-containing protein 2) is also named as AIP2 and belongs to the NEDD4-like protein family. It functions as an E3 ubiquitin ligase for PTEN that plays a vital role in tumour-cell survival and is also involved in regulating transcription, embryonic stem-cell fate, cellular transport and T-cell activation processes (PMID:21532586). WWP2, which specifically interacted with ES cell-specific transcription factor Oct-4 and promoted its ubiquitination both in vitro and in vivo, is a ubiquitously expressed protein and exists in both cytoplasmic and nuclear compartments in ES cells (PMID:15047715).