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WWP2 Monoclonal antibody, PBS Only

WWP2 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2C9B4

Cat no : 67274-1-PBS

Print datasheet

Synonyms

AIP2, WW domain containing protein 2, WWP2, WWp2 like

验证数据展示

  • WB analysis using 67274-1-Ig (same clone as 67274-1-PBS)

    WB analysis using 67274-1-Ig (same clone as 67274-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67274-1-Ig (WWP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67274-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 67274-1-Ig (same clone as 67274-1-PBS)

    IHC staining of human pancreas cancer using 67274-1-Ig (same clone as 67274-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 67274-1-Ig (WWP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67274-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 67274-1-Ig (same clone as 67274-1-PBS)

    IHC staining of human pancreas cancer using 67274-1-Ig (same clone as 67274-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 67274-1-Ig (WWP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67274-1-PBS in a different storage buffer formulation.

产品信息

67274-1-PBS targets WWP2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human, Rat
Immunogen WWP2 fusion protein Ag2835 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name WW domain containing E3 ubiquitin protein ligase 2
Synonyms AIP2, WW domain containing protein 2, WWP2, WWp2 like
Calculated Molecular Weight 870 aa, 99 kDa
Observed Molecular Weight 100-115 kDa
GenBank Accession NumberBC013645
Gene Symbol WWP2
Gene ID (NCBI) 11060
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDO00308
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

WWP2 (WW domain-containing protein 2) is also named as AIP2 and belongs to the NEDD4-like protein family. It functions as an E3 ubiquitin ligase for PTEN that plays a vital role in tumour-cell survival and is also involved in regulating transcription, embryonic stem-cell fate, cellular transport and T-cell activation processes (PMID:21532586). WWP2, which specifically interacted with ES cell-specific transcription factor Oct-4 and promoted its ubiquitination both in vitro and in vivo, is a ubiquitously expressed protein and exists in both cytoplasmic and nuclear compartments in ES cells (PMID:15047715).