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ZMPSTE24 Recombinant antibody, PBS Only

ZMPSTE24 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241288C11

Cat no : 84547-1-PBS

Print datasheet

Synonyms

FACE-1, FACE1, FACE 1, EC:3.4.24.84, CAAX prenyl protease 1 homolog

验证数据展示

  • WB analysis using 84547-1-RR (same clone as 84547-1-PBS)

    WB analysis using 84547-1-RR (same clone as 84547-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84547-1-RR (ZMPSTE24 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84547-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84547-1-RR

    Affinity and Kinetic Characterization of 84547-1-RR

    Biolayer interferometry (BLl) kinetic assays of 84547-1-RR against Human ZMPSTE24 were performed. The affinity constant is 1.87 nM.

Planning an IHC experiment? We recommend our IHCeasy ZMPSTE24 Ready-To-Use IHC Kit. ZMPSTE24 primary antibody included.

产品信息

84547-1-PBS targets ZMPSTE24 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen ZMPSTE24 fusion protein Ag33613 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name zinc metallopeptidase (STE24 homolog, S. cerevisiae)
Synonyms FACE-1, FACE1, FACE 1, EC:3.4.24.84, CAAX prenyl protease 1 homolog
Calculated Molecular Weight 475 aa, 55 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC037283
Gene Symbol ZMPSTE24
Gene ID (NCBI) 10269
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO75844
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ZMPSTE24(CAAX prenyl protease 1 homolog) gene encodes a zinc metalloproteinase involved in the processing of farnesylated proteins(PubMed: 10373325). The significance of ZMPSTE24 in human disease stems from its role as an enzyme necessary for the correct processing and maturation of lamin A ,an intermediate filament component of the nuclear envelope (PubMed: 16297189).