CoraLite® Plus 488-conjugated Zinc Alpha 2 Glycoprotein Monoclonal antibody
Zinc Alpha 2 Glycoprotein Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
4B8A4
验证数据展示
经过测试的应用
Positive IF/ICC detected in | PC-3 cells |
Planning an IHC experiment? We recommend our IHCeasy AZGP1 Ready-To-Use IHC Kit. AZGP1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66178-1-Ig
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-66178 targets Zinc Alpha 2 Glycoprotein in IF/ICC applications and shows reactivity with human samples.
Tested Applications | IF/ICC Application Description |
Tested Reactivity | human |
Immunogen | Zinc Alpha 2 Glycoprotein fusion protein Ag5661 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | alpha-2-glycoprotein 1, zinc-binding |
Synonyms | AZGP1, ZA2G, ZAG, Zinc alpha 2 glycoprotein, Zn alpha 2 glycoprotein, Zn alpha 2 GP, ZNGP1 |
Calculated Molecular Weight | 298 aa, 34 kDa |
Observed Molecular Weight | 41 kDa |
GenBank Accession Number | BC033830 |
Gene Symbol | Zinc Alpha 2 Glycoprotein |
Gene ID (NCBI) | 563 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P25311 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Zinc-alpha-2-glycoprotein (AZGP1) is a 41-kDa soluble protein normally found in body fluids, functions as a lipid mobilizing factor (PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex (MHC) antigens (PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors (PMID: 22625427).
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 Zinc Alpha 2 Glycoprotein antibody CL488-66178 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |