AKT Signaling: New Pathway Poster
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All the posters in the Proteintech library are available in PDF format or can be requested as a hard copy.
Overview: AKT Signaling and Cancer
The serine/threonine kinase B AKT pathway (also known as the PI3K-Akt pathway) plays a vital role in the regulation of cellular processes, including cell proliferation, survival, and growth – processes that are essential for oncogenesis (D Altomare and J Testa, 2005) (Ji Luo et al., 2003).
Mutation of the regulator proteins PI3K and PTEN causes uncontrolled disruption within the PI3-kinase pathway, leading to the development of human cancers. Targeting the deregulation of PI3K/PTEN-Akt signaling has recently emerged as a potential therapy in anticancer drug development (Zhang S and Yu D, 2010).
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Download the AKT signaling pathway poster here |
Related products
| Antibodies | ||
| AKT (KD/KO validated) | p53 (KD/KO validated) | GSK3A |
| AKT1 (KD/KO validated) | MTOR | GSK3B (KD/KO validated) |
| AKT2 | PI3K p110 (alpha) | Raptor (KD/KO validated) |
| AKT3 | PI3K p110 (beta) | CREB1 |
| Caspase 9/P35/P10 | PTEN | GLUT4 |
Browse more pathway posters here |