Notable Publications - May Update

A small selection of recent notable publications from around the world

What matters to Proteintech is the success of its antibodies in the hands of scientists.

Here’s just a small selection of publications featuring Proteintech products from March - May 2017.


1. Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice.

2. 5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader.

3. Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.

4. Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation.

5. Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency.


Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice.

L Becker and B Huang et al

Nature   544, 367–371 (20 April 2017)

Country: US

Institution:  Department of Genetics, Stanford University School of Medicine

Cited products:  TDP-43 (12892-1-AP)

TDP-43 (C-Terminal) Antibody
KD/KO Validated Catalog number: 12892-1-AP
59 Publications Applications: ELISA, chip, IF, IHC, IP, WB

5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader.

X Yang and Y Yang et al

Cell Research (2017) 27:606–625

Country: China

Institution:  Center for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University

Cited Products:  NSUN2 (20854-1-AP)

NSUN2 Antibody
KD/KO Validated Catalog number: 20854-1-AP
7 Publications Applications: ELISA, IF, IHC, IP, WB

Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.

L Romani and V Oikonomou et al

Nature Medicine (2017)

Country: Italy

Institution:  Department of Experimental Medicine, University of Perugia

Cited Products:  USP36 (14783-1-AP)


Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation.

B Slobodin and R Han et al

Cell (6 April 2017) 169:326–337

Country: The Netherlands

Institution: Division of Oncogenomics, Netherlands Cancer Institute

Cited Products:  METTL3 (15073-1-AP)

METTL3 Antibody  
KD/KO Validated Catalog number: 15073-1-AP
12 Publications Applications: ELISA, IF, IHC, IP, WB

Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency.

Cottineau J and Kottemann MC et al

J Clin Invest. 2017 May 1;127(5):1991-2006

Country: France

Institution:  Laboratory of Human Genetics of Infectious Diseases

Cited Products:  GINS3 (15651-1-AP)