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验证数据展示

  • WB analysis of Raji using 84913-1-RR (same clone as 84913-1-PBS)

    WB analysis of Raji using 84913-1-RR (same clone as 84913-1-PBS)

    Raji cells were subjected to SDS PAGE followed by western blot with 84913-1-RR (IMPDH1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84913-1-PBS in a different storage buffer formulation.

  • WB analysis using 84913-1-RR (same clone as 84913-1-PBS)

    WB analysis using 84913-1-RR (same clone as 84913-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84913-1-RR (IMPDH1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84913-1-PBS in a different storage buffer formulation.

  • Sandwich ELISA standard curve of MP01726-1

    Sandwich ELISA standard curve of MP01726-1

    Sandwich ELISA standard curve of MP01726-1, Human IMPDH1 Recombinant Matched Antibody Pair - PBS only. 84913-1-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Ag17473. 84913-2-PBS was HRP conjugated as the detection antibody. Range: 0.156-10 ng/mL.

  • Sample test of MP01726-1

    Sample test of MP01726-1

    The mean IMPDH1 concentration was determined to be 27.79 ng/mL in HeLa cell extract based on a 1.00 mg/mL extract load and 45.02 ng/mL in A431 cell extract based on a 1.30 mg/mL extract load.

  • Affinity and Kinetic Characterization of 84913-1-RR

    Affinity and Kinetic Characterization of 84913-1-RR

    Biolayer interferometry (BLl) kinetic assays of 84913-1-RR against Human IMPDH1 were performed. The affinity constant is 4.41 nM.

IMPDH1 Recombinant antibody, PBS Only (Capture)

IMPDH1 Uni-rAbTM Recombinant Antibody for WB, Sandwich ELISA, Indirect ELISA, Sample test
Cat No. 84913-1-PBS

产品说明书

CloneNo. 242329D8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Sandwich ELISA, Indirect ELISA, Sample test

别名

IMPDH 1, IMPD1, IMPD 1, IMP dehydrogenase 1, EC:1.1.1.205

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy IMPDH1 Ready-To-Use IHC Kit. IMPDH1 primary antibody included.

产品信息

84913-1-PBS targets IMPDH1 as part of a matched antibody pair:

MP01726-1: 84913-1-PBS capture and 84913-2-PBS detection (validated in Sandwich ELISA)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Sandwich ELISA, Indirect ELISA, Sample test Application Description
经测试反应性 human
免疫原 IMPDH1 fusion protein Ag17473 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 IMP (inosine monophosphate) dehydrogenase 1
别名 IMPDH 1, IMPD1, IMPD 1, IMP dehydrogenase 1, EC:1.1.1.205
计算分子量 563 aa, 60 kDa
观测分子量53-60 kDa
GenBank蛋白编号BC033622
基因名称 IMPDH1
Gene ID (NCBI) 3614
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP20839
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IMPDH1(Inosine-5'-monophosphate dehydrogenase 1) is also named as IMPD1, IMP dehydrogenase 1 and belongs to the IMPDH/GMPR family. It catalyzes the rate limiting step of de novo guanine synthesis and an important target for the development of drugs with both chemotherapeutic and immunosuppressive activity. It may also have a role in the development of malignancy and the growth progression of some tumors. This protein has some isoforms produced by alternative splicing with the molecular mass of 53-65 kDa.