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验证数据展示

  • IF Staining of HeLa using CL488-66464

    IF Staining of HeLa using CL488-66464

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using CoraLite® Plus 488 ADRM1 antibody (CL488-66464, Clone: 1A1A3 ) at dilution of 1:200.

CoraLite® Plus 488-conjugated ADRM1 Monoclonal antibody

ADRM1 Monoclonal Antibody for IF/ICC
Cat No. CL488-66464

产品说明书

CloneNo. 1A1A3

宿主/亚型

Mouse / IgG3

种属反应性

human

应用

IF/ICC

别名

adhesion regulating molecule 1, ADRM1, ARM 1, ARM1, GP110, hRpn13, Rpn13, Rpn13 homolog

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -

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经过测试的应用

Positive IF/ICC detected inHeLa cells
Planning an IHC experiment? We recommend our IHCeasy ADRM1 Ready-To-Use IHC Kit. ADRM1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66464-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-66464 targets ADRM1 in IF/ICC applications and shows reactivity with human samples.

经测试应用 IF/ICC Application Description
经测试反应性 human
免疫原 ADRM1 fusion protein Ag24699 种属同源性预测
宿主/亚型 Mouse / IgG3
抗体类别 Monoclonal
产品类型 Antibody
全称 adhesion regulating molecule 1
别名 adhesion regulating molecule 1, ADRM1, ARM 1, ARM1, GP110, hRpn13, Rpn13, Rpn13 homolog
计算分子量 407 aa, 42 kDa
观测分子量 42 kDa
GenBank蛋白编号BC017245
基因名称 ADRM1
Gene ID (NCBI) 11047
RRIDAB_2934463
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ16186
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The 26S proteasome is a key component of the ubiquitin-proteasome system, a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme, UCH37, and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 ADRM1 antibody CL488-66464Download protocol
Standard Protocols
Click here to view our Standard Protocols