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验证数据展示

  • IF Staining of HeLa using CL594-66464

    IF Staining of HeLa using CL594-66464

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using CoraLite®594 ADRM1 antibody (CL594-66464, Clone: 1A1A3 ) at dilution of 1:200.

CoraLite®594-conjugated ADRM1 Monoclonal antibody

ADRM1 Monoclonal Antibody for IF/ICC
Cat No. CL594-66464

Print datasheet

CloneNo. 1A1A3

Host / Isotype

Mouse / IgG3

Reactivity

human

Applications

IF/ICC

Synonyms

adhesion regulating molecule 1, ADRM1, ARM 1, ARM1, GP110, hRpn13, Rpn13, Rpn13 homolog

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  CoraLite®594
Size: 

-/ -

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经过测试的应用

Positive IF/ICC detected inHeLa cells
Planning an IHC experiment? We recommend our IHCeasy ADRM1 Ready-To-Use IHC Kit. ADRM1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66464-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-66464 targets ADRM1 in IF/ICC applications and shows reactivity with human samples.

Tested Applications IF/ICC Application Description
Tested Reactivity human
Immunogen ADRM1 fusion protein Ag24699 种属同源性预测
Host / Isotype Mouse / IgG3
Class Monoclonal
Type Antibody
Full Name adhesion regulating molecule 1
Synonyms adhesion regulating molecule 1, ADRM1, ARM 1, ARM1, GP110, hRpn13, Rpn13, Rpn13 homolog
Calculated Molecular Weight 407 aa, 42 kDa
Observed Molecular Weight 42 kDa
GenBank Accession NumberBC017245
Gene Symbol ADRM1
Gene ID (NCBI) 11047
RRIDAB_2934726
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission Maxima Wavelengths588 nm / 604 nm
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ16186
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The 26S proteasome is a key component of the ubiquitin-proteasome system, a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme, UCH37, and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.

实验方案

Product Specific Protocols
IF protocol for CL594 ADRM1 antibody CL594-66464Download protocol
Standard Protocols
Click here to view our Standard Protocols