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验证数据展示

  • IF Staining of HeLa using CL594-66464

    IF Staining of HeLa using CL594-66464

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using CoraLite®594 ADRM1 antibody (CL594-66464, Clone: 1A1A3 ) at dilution of 1:200.

CoraLite®594-conjugated ADRM1 Monoclonal antibody

ADRM1 Monoclonal Antibody for IF/ICC
Cat No. CL594-66464

产品说明书

CloneNo. 1A1A3

宿主/亚型

Mouse / IgG3

种属反应性

human

应用

IF/ICC

别名

adhesion regulating molecule 1, ADRM1, ARM 1, ARM1, GP110, hRpn13, Rpn13, Rpn13 homolog

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite®594
规格: 

-/ -

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经过测试的应用

Positive IF/ICC detected inHeLa cells
Planning an IHC experiment? We recommend our IHCeasy ADRM1 Ready-To-Use IHC Kit. ADRM1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66464-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-66464 targets ADRM1 in IF/ICC applications and shows reactivity with human samples.

经测试应用 IF/ICC Application Description
经测试反应性 human
免疫原 ADRM1 fusion protein Ag24699 种属同源性预测
宿主/亚型 Mouse / IgG3
抗体类别 Monoclonal
产品类型 Antibody
全称 adhesion regulating molecule 1
别名 adhesion regulating molecule 1, ADRM1, ARM 1, ARM1, GP110, hRpn13, Rpn13, Rpn13 homolog
计算分子量 407 aa, 42 kDa
观测分子量 42 kDa
GenBank蛋白编号BC017245
基因名称 ADRM1
Gene ID (NCBI) 11047
RRIDAB_2934726
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ16186
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The 26S proteasome is a key component of the ubiquitin-proteasome system, a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme, UCH37, and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.

实验方案

Product Specific Protocols
IF protocol for CL594 ADRM1 antibody CL594-66464Download protocol
Standard Protocols
Click here to view our Standard Protocols