验证数据展示
产品信息
67320-1-PBS targets ARPC1B in WB, IHC, Indirect ELISA applications and shows reactivity with Human, rat, mouse samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | Human, rat, mouse |
免疫原 | ARPC1B fusion protein Ag29095 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | actin related protein 2/3 complex, subunit 1B, 41kDa |
别名 | ARC41, Arp2/3 complex 41 kDa subunit, ARPC1B, p40 ARC, p41 ARC |
计算分子量 | 41 kDa |
观测分子量 | 38 kDa |
GenBank蛋白编号 | BC007555 |
基因名称 | ARPC1B |
Gene ID (NCBI) | 10095 |
RRID | AB_2882580 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | O15143 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ARPC1B also known as ARC41, p41-ARC, or p40-ARC, is one of seven subunits of the human Arp2/3 protein complex, that belongs to the SOP2 family. ARPC1B localizes on centrosomes and has a distinct role in centrosomal homeostasis. ARPC1B is both a physiological activator and substrate of Aurora A kinase, and these interactions help to maintain mitotic integrity in mammalian cells. In recent resaeach, ARPC1B is selected as a candidate prediction marker for sensitivity of Choroidal malignant melanomas to radiotherapy.