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Beta-2-Microglobulin Recombinant antibody, PBS Only

Beta-2-Microglobulin Uni-rAbTM Recombinant Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IP, ELISA

Conjugate

Unconjugated

CloneNo.

240660A12

Cat no : 83683-6-PBS

Print datasheet

Synonyms

B2M, 240660A12, HDCMA22P, CDABP0092, Beta-2-microglobulin form pI 5.3

验证数据展示

  • WB analysis using 83683-6-RR (same clone as 83683-6-PBS)

    WB analysis using 83683-6-RR (same clone as 83683-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83683-6-RR (Beta-2-Microglobulin antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83683-6-PBS in a different storage buffer formulation.

  • IP experiment of A431 using 83683-6-RR (same clone as 83683-6-PBS)

    IP experiment of A431 using 83683-6-RR (same clone as 83683-6-PBS)

    IP result of anti-Beta-2-Microglobulin (IP:83683-6-RR, 4ug; Detection:83683-6-RR 1:3000) with A431 cells lysate 2180 ug. This data was developed using the same antibody clone with 83683-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83683-6-RR

    Affinity and Kinetic Characterization of 83683-6-RR

    Biolayer interferometry (BLl) kinetic assays of 83683-6-RR against Human Beta-2-Microglobulin were performed. The affinity constant is 1.18 nM.

Planning an IHC experiment? We recommend our IHCeasy Beta-2-Microglobulin Ready-To-Use IHC Kit. Beta-2-Microglobulin primary antibody included.

产品信息

83683-6-PBS targets Beta-2-Microglobulin in WB, IP, ELISA applications and shows reactivity with human samples.

Tested Applications WB, IP, ELISA Application Description
Tested Reactivity human
Immunogen Beta-2-Microglobulin fusion protein Ag4433 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name beta-2-microglobulin
Synonyms B2M, 240660A12, HDCMA22P, CDABP0092, Beta-2-microglobulin form pI 5.3
Calculated Molecular Weight 119 aa, 14 kDa
Observed Molecular Weight 12 kDa
GenBank Accession NumberBC032589
Gene Symbol B2M
Gene ID (NCBI) 567
ENSEMBL Gene IDENSG00000166710
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP61769
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Beta-2-microglobulin (B2M) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions due to shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.