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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of Jurkat using 67260-1-Ig (same clone as 67260-1-PBS)

    WB analysis of Jurkat using 67260-1-Ig (same clone as 67260-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 67260-1-Ig (BCR antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67260-1-PBS in a different storage buffer formulation.

  • FC experiment of K-562 using 67260-1-Ig (same clone as 67260-1-PBS)

    FC experiment of K-562 using 67260-1-Ig (same clone as 67260-1-PBS)

    1X10^6 K-562 cells were intracellularly stained with 0.4 ug Anti-Human BCR (67260-1-Ig, Clone:2C2E3) and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (red), or 0.4 ug Mouse IgG2b Isotype Control (66360-3-Ig, Clone: K11B8C4B5) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 67260-1-PBS in a different storage buffer formulation.

BCR Monoclonal antibody, PBS Only

BCR Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67260-1-PBS

产品说明书

CloneNo. 2C2E3

宿主/亚型

Mouse / IgG2b

种属反应性

Human, rat

应用

WB, Indirect ELISA

别名

ALL, BCR, breakpoint cluster region, CML, D22S11, D22S662, FLJ16453, PHL

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy BCR Ready-To-Use IHC Kit. BCR primary antibody included.

产品信息

67260-1-PBS targets BCR in WB, Indirect ELISA applications and shows reactivity with Human, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, rat
免疫原 BCR fusion protein Ag28953 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 breakpoint cluster region
别名 ALL, BCR, breakpoint cluster region, CML, D22S11, D22S662, FLJ16453, PHL
计算分子量 143 kDa
观测分子量 150-160 kDa
GenBank蛋白编号BC066122
基因名称 BCR
Gene ID (NCBI) 613
RRIDAB_2882531
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP11274
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The Bcr gene, mapping on chromosome22, was orginally identified by its presence in the chimeric Bcr-Abl oncogene. The Bcr gene encodes for the break point cluster region protein(Bcr). Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for RAC1 and CDC42. A chromosomal aberration involving BCR has been found in patients with chronic myeloid leukemia.