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CoraLite®594-conjugated BRE Monoclonal antibody

BRE Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG2a

Reactivity

human, rat, mouse

Applications

IF

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

2E5A5

Cat No : CL594-66356

Print datasheet

Synonyms

BRCA1 A complex subunit BRE, BRCC4, BRCC45, BRE

验证数据展示

  • IF Staining of mouse brain using CL594-66356

    IF Staining of mouse brain using CL594-66356

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite®594 BRE antibody (CL594-66356, Clone: 2E5A5 ) at dilution of 1:200.

经过测试的应用

Positive IF detected inmouse brain tissue
For other applications, we recommend the unconjugated version of this antibody, 66356-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-66356 targets BRE in IF applications and shows reactivity with human, rat, mouse samples.

Tested Applications IF Application Description
Tested Reactivity human, rat, mouse
Immunogen BRE fusion protein Ag2256 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name brain and reproductive organ-expressed (TNFRSF1A modulator)
Synonyms BRCA1 A complex subunit BRE, BRCC4, BRCC45, BRE
Calculated Molecular Weight 383 aa, 44 kDa
Observed Molecular Weight 42-47 kDa
GenBank Accession NumberBC001251
Gene Symbol BRE
Gene ID (NCBI) 9577
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission Maxima Wavelengths588 nm / 604 nm
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9NXR7
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

BRE, also named as BRCC45, is a death receptor-associated antiapoptotic protein, which is also involved in DNA-damage repair, and K63-specific deubiquitination. BRE and its XIAP-sustaining mechanism could represent novel targets for anti-cancer therapy. BRE may regulate TNF-alpha signaling through its interactions with TNFRSF1A. It plays a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. BRE gene has four isoforms with MW 42-47 kDa.

实验方案

Product Specific Protocols
IF protocol for CL594 BRE antibody CL594-66356Download protocol
Standard Protocols
Click here to view our Standard Protocols