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BVES Polyclonal antibody

BVES Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 12920-1-AP

Print datasheet

Synonyms

BVES, HBVES, POP1, POPDC1, Popeye protein 1

验证数据展示

  • WB analysis of mouse skeletal muscle using 12920-1-AP

    WB analysis of mouse skeletal muscle using 12920-1-AP

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 12920-1-AP (BVES antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  • IHC staining of human ovary tumor using 12920-1-AP

    IHC staining of human ovary tumor using 12920-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 12920-1-AP (BVES antibody) at dilution of 1:100 (under 10x lens).

经过测试的应用

Positive WB detected inmouse skeletal muscle tissue
Positive IHC detected inhuman ovary tumor tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

12920-1-AP targets BVES in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, ELISA Application Description
Cited ApplicationsWB, IHC
Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Immunogen BVES fusion protein Ag3593 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name blood vessel epicardial substance
Synonyms BVES, HBVES, POP1, POPDC1, Popeye protein 1
Calculated Molecular Weight 360 aa, 41 kDa
Observed Molecular Weight 41-70 kDa
GenBank Accession NumberBC034425
Gene Symbol BVES
Gene ID (NCBI) 11149
RRIDAB_10640584
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8NE79
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

BVES, also named as POP1, POPDC1 and hBVES, belongs to the popeye family. It is cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. It is involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. It is also involved in striated muscle regeneration and repair and in the regulation of cell spreading. BVES is expressed in the progenitors of coronary artery smooth muscle cells as well as in differentiated smooth muscle cells.

实验方案

Product Specific Protocols
WB protocol for BVES antibody 12920-1-APDownload protocol
IHC protocol for BVES antibody 12920-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Oncol Rep

MBNL1‑AS1 attenuates tumor cell proliferation by regulating the miR‑29c‑3p/BVES signal in colorectal cancer

Authors - Wang-Sheng Chen
View Article
humanIHC

Pathol Oncol Res

Abnormal expression of adhesion protein Bves is associated with gastric cancer progression and poor survival.

Authors - Luo Deng D
View Article