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Host
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Species Reactivity
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Species Reactivity
0
Conjugate
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验证数据展示

  • FC experiment of THP-1 using 98221-1-RR (same clone as 98221-1-PBS)

    FC experiment of THP-1 using 98221-1-RR (same clone as 98221-1-PBS)

    1x10^6 PMA, LPS and Brefeldin A treated THP-1 cells were intracellularly stained with 0.25 ug Anti-Human CCL20/MIP-3 alpha Rabbit Recombinant Antibody (98221-1-RR, Clone: 241694B2) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). 1x10^6 untreated THP-1 cells were intracellularly stained with 0.25 ug Anti-Human CCL20/MIP-3 alpha Rabbit Recombinant Antibody (98221-1-RR, Clone: 241694B2) (black, dashed) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98221-1-PBS in a different storage buffer formulation.

Anti-Human CCL20/MIP-3 alpha Rabbit Recombinant Antibody, PBS Only

CCL20/MIP-3 alpha Uni-rAbTM Recombinant Antibody for FC (Intra)
Cat No. 98221-1-PBS

产品说明书

CloneNo. 241694B2

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC (Intra)

别名

CCL20, MIP-3 Alpha, MIP-3α, CCL 20, C-C motif chemokine 20

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CCL20/MIP3A Ready-To-Use IHC Kit. CCL20/MIP3A primary antibody included.

产品信息

98221-1-PBS targets CCL20/MIP-3 alpha in FC (Intra) applications and shows reactivity with human samples.

经测试应用 FC (Intra) Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 chemokine (C-C motif) ligand 20
别名 CCL20, MIP-3 Alpha, MIP-3α, CCL 20, C-C motif chemokine 20
计算分子量11kDa
GenBank蛋白编号NM_004591.3
基因名称 CCL20/MIP-3 alpha
Gene ID (NCBI) 6364
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP78556-1
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17 (Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells (DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease (COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.