PE-Cyanine7 Anti-Mouse CD11b (M1/70)
CD11b Monoclonal Antibody for FC
Host / Isotype
Rat / IgG2b, kappa
Reactivity
Mouse, Human
Applications
FC
Conjugate
PE-Cyanine7 Fluorescent Dye
CloneNo.
M1/70
验证数据展示
产品信息
PE-Cyanine7-65055 targets CD11b in FC applications and shows reactivity with Mouse, Human samples.
| Tested Applications | FC Application Description |
| Tested Reactivity | Mouse, Human |
| Immunogen | C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes 种属同源性预测 |
| Host / Isotype | Rat / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | integrin alpha M |
| Synonyms | Cd11b, CD11b/CD18, CR3, CR3A, F730045J24Rik, integrin alpha M, Itgam, Ly 40, Mac 1, Mac 1a, MAC1 |
| GenBank Accession Number | BC156991 |
| Gene Symbol | Itgam |
| Gene ID (NCBI) | 16409 |
| Conjugate | PE-Cyanine7 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 450-500 nm / 778 nm |
| Form | Liquid |
| Purification Method | Affinity purification |
| UNIPROT ID | E9Q604 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for PE-Cyanine7 CD11b antibody PE-Cyanine7-65055 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |