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PE-Cyanine7 Anti-Mouse CD11b (M1/70)

CD11b Monoclonal Antibody for FC

Host / Isotype

Rat / IgG2b, kappa

Reactivity

Mouse, Human

Applications

FC

Conjugate

PE-Cyanine7 Fluorescent Dye

CloneNo.

M1/70

Cat no : PE-Cyanine7-65055

Print datasheet

Synonyms

Cd11b, CD11b/CD18, CR3, CR3A, F730045J24Rik, integrin alpha M, Itgam, Ly 40, Mac 1, Mac 1a, MAC1

验证数据展示

产品信息

PE-Cyanine7-65055 targets CD11b in applications and shows reactivity with Mouse, Human samples.

Tested Applications FC Application Description
Tested Reactivity Mouse, Human
Immunogen C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes 种属同源性预测
Host / Isotype Rat / IgG2b, kappa
Class Monoclonal
Type Antibody
Full Name integrin alpha M
Synonyms Cd11b, CD11b/CD18, CR3, CR3A, F730045J24Rik, integrin alpha M, Itgam, Ly 40, Mac 1, Mac 1a, MAC1
Calculated Molecular Weight127 kDa
GenBank Accession NumberBC156991
Gene Symbol CD11b
Gene ID (NCBI) 16409
Conjugate PE-Cyanine7 Fluorescent Dye
Excitation/Emission Maxima Wavelengths450-500 nm / 778 nm
Form Liquid
Purification MethodAffinity purification
UNIPROT IDE9Q604
Storage Buffer PBS with 0.09% sodium azide and 0.5% BSA.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).

实验方案

Product Specific Protocols
FC protocol for PE-Cyanine7 CD11b antibody PE-Cyanine7-65055Download protocol
Standard Protocols
Click here to view our Standard Protocols