Anti-Mouse CD134/OX40 (OX-86)

CD134/OX40 Monoclonal Antibody for FC
Cat No. 65136-1-Ig

产品说明书

CloneNo. OX-86

宿主/亚型

Rat / IgG1, kappa

种属反应性

mouse

应用

FC

Tnfrsf4, CD134, Txgp1, OX-86, Ox40

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inCon-A stimulated mouse splenocytes

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

65136-1-Ig targets CD134/OX40 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 N/A 种属同源性预测
宿主/亚型 Rat / IgG1, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 4
别名 Tnfrsf4, CD134, Txgp1, OX-86, Ox40
GenBank蛋白编号BC065782
基因名称 CD134
Gene ID (NCBI) 22163
RRIDAB_2918423
偶联类型 Unconjugated
形式 Liquid
纯化方式Affinity purification
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Stable for one year after shipment.

背景介绍

CD134, also known as OX40 and TNFRSF4, is a member of the TNFR-superfamily of receptors (PMID: 2828930; 9766631). It is a type I transmembrane protein predominantly expressed on activated T cells which include CD4 and CD8 T cells, Th2, Th1, and Th17 cells, as well as regulatory T cells (Tregs) (PMID: 20307208). CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule (PMID: 26215166). CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmune diseases, cancer and infectious disease (PMID: 26215166; 19426222).

实验方案

Product Specific Protocols
FC protocol for CD134/OX40 antibody 65136-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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