APC Anti-Mouse CD134/OX40 (OX-86)

CD134/OX40 Monoclonal Antibody for FC
Cat No. APC-65136

产品说明书

CloneNo. OX-86

宿主/亚型

Rat / IgG1, kappa

种属反应性

mouse

应用

FC

Tnfrsf4, CD134, Txgp1, OX-86, Ox40

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inAnti-CD3/CD28 treated mouse splenocytes

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

FCSee 1 publications below

产品信息

APC-65136 targets CD134/OX40 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
文献引用应用FC
经测试反应性 mouse
文献引用反应性mouse
免疫原 Recombinant mouse OX-40-CD4 chimeric protein 种属同源性预测
宿主/亚型 Rat / IgG1, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 4
别名 Tnfrsf4, CD134, Txgp1, OX-86, Ox40
GenBank蛋白编号BC065782
基因名称 CD134
Gene ID (NCBI) 22163
RRIDAB_2883017
偶联类型 APC Fluorescent Dye
最大激发/发射波长650 nm / 660 nm
形式 Liquid
纯化方式Affinity purification
UNIPROT IDP47741
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

CD134, also known as OX40 and TNFRSF4, is a member of the TNFR-superfamily of receptors (PMID: 2828930; 9766631). It is a type I transmembrane protein predominantly expressed on activated T cells which include CD4 and CD8 T cells, Th2, Th1, and Th17 cells, as well as regulatory T cells (Tregs) (PMID: 20307208). CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule (PMID: 26215166). CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmune diseases, cancer and infectious disease (PMID: 26215166; 19426222).

实验方案

Product Specific Protocols
FC protocol for APC CD134/OX40 antibody APC-65136Download protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseFC

Biomed Res

Blockade of CD80/CD86-CD28 co-stimulation augments the inhibitory function of peptide antigen-specific regulatory T cells

Authors - Yui Maehara
Loading...