CoraLite® Plus 555 Anti-Mouse CD134/OX40 (OX-86)

CD134/OX40 Monoclonal Antibody for FC
Cat No. CL555-65136

产品说明书

CloneNo. OX-86

宿主/亚型

Rat / IgG1, kappa

种属反应性

mouse

应用

FC

Tnfrsf4, CD134, Txgp1, OX-86, Ox40

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inAnti-CD3/CD28 treated mouse splenocytes
For other applications, we recommend the unconjugated version of this antibody, 65136-1-Ig

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL555-65136 targets CD134/OX40 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 N/A 种属同源性预测
宿主/亚型 Rat / IgG1, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 4
别名 Tnfrsf4, CD134, Txgp1, OX-86, Ox40
GenBank蛋白编号BC065782
基因名称 CD134
Gene ID (NCBI) 22163
RRIDAB_3084559
偶联类型 CoraLite® Plus 555 Fluorescent Dye
最大激发/发射波长554 nm / 570 nm
形式 Liquid
纯化方式Affinity purification
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

CD134, also known as OX40 and TNFRSF4, is a member of the TNFR-superfamily of receptors (PMID: 2828930; 9766631). It is a type I transmembrane protein predominantly expressed on activated T cells which include CD4 and CD8 T cells, Th2, Th1, and Th17 cells, as well as regulatory T cells (Tregs) (PMID: 20307208). CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule (PMID: 26215166). CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmune diseases, cancer and infectious disease (PMID: 26215166; 19426222).

实验方案

Product Specific Protocols
FC protocol for CL Plus 555 CD134/OX40 antibody CL555-65136Download protocol
Standard Protocols
Click here to view our Standard Protocols
Loading...