FITC Plus Anti-Mouse CD31 (390)

CD31 Monoclonal Antibody for IF/ICC, FC
Cat No. FITC-65058

产品说明书

CloneNo. 390

宿主/亚型

Rat / IgG2a, kappa

种属反应性

mouse

应用

IF/ICC, FC and More (1)

PECAM-1, Pecam1, PECAM 1, Pecam, 390

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive IF/ICC detected inbEnd.3 cells
Positive FC detected inmouse bone marrow cells

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

FITC-65058 targets CD31 in IF/ICC, FC applications and shows reactivity with mouse samples.

经测试应用 IF/ICC, FC Application Description
文献引用应用IF, FC
经测试反应性 mouse
文献引用反应性mouse
免疫原 C3H/HeJ mouse hematopoietic progenitor cell line 32D 种属同源性预测
宿主/亚型 Rat / IgG2a, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 platelet/endothelial cell adhesion molecule 1
别名 PECAM-1, Pecam1, PECAM 1, Pecam, 390
GenBank蛋白编号BC008519
基因名称 CD31
Gene ID (NCBI) 18613
RRIDAB_2883748
偶联类型 FITC Plus Fluorescent Dye
最大激发/发射波长495 nm / 524 nm
形式 Liquid
纯化方式Affinity purification
UNIPROT IDQ08481
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).

实验方案

Product Specific Protocols
IF protocol for FITC Plus CD31 antibody FITC-65058Download protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseIF

Cell Death Dis

LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.

Authors - Hong Su
mouseFC

Bone

mTORC1 coordinates NF-κB signaling pathway to promote chondrogenic differentiation of tendon cells in heterotopic ossification

Authors - Jiaming Fu
FC

Cells

Enhancement of Tendon Repair Using Tendon-Derived Stem Cells in Small Intestinal Submucosa via M2 Macrophage Polarization

Authors - Xufeng Mao
mouseFC

Biochim Biophys Acta Mol Cell Res

CARM1 deficiency inhibits osteoblastic differentiation of bone marrow mesenchymal stem cells and delays osteogenesis in mice

Authors - Jing-Yi Li
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