PE Anti-Mouse CD31 (390)

CD31 Monoclonal Antibody for FC
Cat No. PE-65058

产品说明书

CloneNo. 390

宿主/亚型

Rat / IgG2a, kappa

种属反应性

mouse

应用

FC

Pecam1, PECAM 1, Pecam, 390

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inmouse bone marrow cells

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

PE-65058 targets CD31 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 C3H/HeJ mouse hematopoietic progenitor cell line 32D 种属同源性预测
宿主/亚型 Rat / IgG2a, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 platelet/endothelial cell adhesion molecule 1
别名 Pecam1, PECAM 1, Pecam, 390
GenBank蛋白编号BC008519
基因名称 CD31
Gene ID (NCBI) 18613
RRIDAB_2883855
偶联类型 PE Fluorescent Dye
最大激发/发射波长496 nm, 565 nm / 578 nm
形式 Liquid
纯化方式Affinity purification
UNIPROT IDQ08481
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).

实验方案

Product Specific Protocols
FC protocol for PE CD31 antibody PE-65058Download protocol
Standard Protocols
Click here to view our Standard Protocols
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