FITC Plus Anti-Mouse CD48 (HM48-1)

CD48 Monoclonal Antibody for FC
Cat No. FITC-65227

产品说明书

CloneNo. HM48-1

宿主/亚型

Armenian Hamster / IgG

种属反应性

mouse

应用

FC

MEM 102, HM48-1, CD48 antigen, BLAST1, BLAST 1

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inmouse splenocytes

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

FITC-65227 targets CD48 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Mouse T lymphoma MBL-2 种属同源性预测
宿主/亚型 Armenian Hamster / IgG
抗体类别 Monoclonal
产品类型 Antibody
全称 CD48 antigen
别名 MEM 102, HM48-1, CD48 antigen, BLAST1, BLAST 1
GenBank蛋白编号BC060977
基因名称 Cd48
Gene ID (NCBI) 12506
RRIDAB_2924144
偶联类型 FITC Plus Fluorescent Dye
最大激发/发射波长495 nm / 524 nm
形式 Liquid
纯化方式Affinity purification
UNIPROT IDP18181
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

Signaling lymphocytic activation molecule family 2 (SLAMF2, CD48) is an adhesion and costimulatory molecule expressed constitutively on most hematopoietic cells, particularly in antigen-presenting cells (APC). CD48 is expressed on all the hematopoietic cells, both in humans and mice, except for murine neutrophils and long-term HSC. CD48 exists as both a membrane-bound (mCD48) and a soluble (sCD48) form. CD48 can activate T cells, antigen-presenting cells and granulocytes, by binding to CD2 or bacterial FimH, and through cell intrinsic effects. Interactions between CD48 and its high-affinity ligand CD244 are more complex, with both stimulatory and inhibitory outcomes. CD48 expression is increased in autoimmunity and allergy diseases, and anti-CD48 monoclonal antibodies have been shown to attenuate experimental autoimmune encephalomyelitis.

实验方案

Product Specific Protocols
FC protocol for FITC Plus CD48 antibody FITC-65227Download protocol
Standard Protocols
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