CoraLite® Plus 488-conjugated Calretinin Monoclonal antibody
Calretinin Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, pig, rat
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2D7A9
验证数据展示
经过测试的应用
| Positive IF/ICC detected in | SH-SY5Y cells |
Planning an IHC experiment? We recommend our IHCeasy Calretinin Ready-To-Use IHC Kit. Calretinin primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66496-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-66496 targets Calretinin in IF/ICC applications and shows reactivity with Human, mouse, pig, rat samples.
| Tested Applications | IF/ICC Application Description |
| Tested Reactivity | Human, mouse, pig, rat |
| Immunogen | Calretinin fusion protein Ag2924 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | calbindin 2 |
| Synonyms | 29 kDa calbindin, CAB29, CAL2, CALB2, calbindin 2, Calretinin, CR |
| Calculated Molecular Weight | 29 kDa |
| Observed Molecular Weight | 29 kDa |
| GenBank Accession Number | BC015484 |
| Gene Symbol | Calretinin |
| Gene ID (NCBI) | 794 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P22676 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Calbindin 2 (calretinin), is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Calretinin is a useful marker for differentiating malignant mesothelioma from carcinomas.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 Calretinin antibody CL488-66496 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |