验证数据展示
经过测试的应用
Positive IF-P detected in | human appendicitis tissue |
Positive IF/ICC detected in | SH-SY5Y cells |
推荐稀释比
应用 | 推荐稀释比 |
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Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL555-66496 targets Calretinin in IF/ICC, IF-P applications and shows reactivity with human, mouse, rat, pig samples.
经测试应用 | IF/ICC, IF-P Application Description |
经测试反应性 | human, mouse, rat, pig |
免疫原 | Calretinin fusion protein Ag2924 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | calbindin 2 |
别名 | CALB2, calbindin 2, CAL2, CAB29, 2D7A9 |
计算分子量 | 29 kDa |
观测分子量 | 29 kDa |
GenBank蛋白编号 | BC015484 |
基因名称 | Calretinin |
Gene ID (NCBI) | 794 |
RRID | AB_2919687 |
偶联类型 | CoraLite®555 Fluorescent Dye |
最大激发/发射波长 | 557 nm / 570 nm |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P22676 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Calbindin 2 (calretinin), is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Calretinin is a useful marker for differentiating malignant mesothelioma from carcinomas.
实验方案
Product Specific Protocols | |
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IF protocol for CL555 Calretinin antibody CL555-66496 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |