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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • WB analysis using 84978-1-RR (same clone as 84978-1-PBS)

    WB analysis using 84978-1-RR (same clone as 84978-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84978-1-RR (KRT17-Specific antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84978-1-PBS in a different storage buffer formulation.

  • IHC staining of human skin cancer using 84978-1-RR (same clone as 84978-1-PBS)

    IHC staining of human skin cancer using 84978-1-RR (same clone as 84978-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 84978-1-RR (Cytokeratin 17-specific antibody) at dilution of 1:6000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84978-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with KRT17 antibody included
  • IF Staining of HeLa using 84978-1-RR (same clone as 84978-1-PBS)

    IF Staining of HeLa using 84978-1-RR (same clone as 84978-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using Cytokeratin 17-Specific antibody (84978-1-RR, Clone: 242240A8 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84978-1-PBS in a different storage buffer formulation.

  • IHC staining of human skin cancer using 84978-1-RR (same clone as 84978-1-PBS)

    IHC staining of human skin cancer using 84978-1-RR (same clone as 84978-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 84978-1-RR (Cytokeratin 17-specific antibody) at dilution of 1:6000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84978-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with KRT17 antibody included
  • FC experiment of HeLa using 84978-1-RR (same clone as 84978-1-PBS)

    FC experiment of HeLa using 84978-1-RR (same clone as 84978-1-PBS)

    1x10^6 HeLa cells were intracellularly stained with 0.25 ug Cytokeratin 17-specific Recombinant antibody (84978-1-RR, Clone:242240A8) and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2)(red), or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 84978-1-PBS in a different storage buffer formulation.

Cytokeratin 17-specific Recombinant antibody, PBS Only

Cytokeratin 17-specific Uni-rAbTM Recombinant Antibody for WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Cat No. 84978-1-PBS

产品说明书

CloneNo. 242240A8

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, FC (Intra), Indirect ELISA

别名

Cytokeratin 17, KRT17, 242240A8, CK 17, CK-17

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy KRT17 Ready-To-Use IHC Kit. KRT17 primary antibody included.

产品信息

84978-1-PBS targets Cytokeratin 17-specific in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, FC (Intra), Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 keratin 17
别名 Cytokeratin 17, KRT17, 242240A8, CK 17, CK-17
计算分子量 48 kDa
观测分子量48 kDa
GenBank蛋白编号NM_000422
基因名称 Cytokeratin 17
Gene ID (NCBI) 3872
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ04695
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Keratins are a large family of proteins that form the intermediate filaments that make up the cytoskeleton. Type I keratins are a group of acidic intermediate filament proteins and type II keratins are the basic or neutral counterparts. Keratin 17 is encoded by the KRT17 gene and is a type I cytokeratin found in nail beds, hair follicles, sebaceous glands, and epidermal appendages.The molecular weight of cytokeratin 17 is approximately 49 kDa.Cytokeratin 17 plays a role in the formation and maintenance of epidermal appendages, especially in determining the shape and orientation of hair. It is required for the maintenance of the anagen (growth) state of hair follicles by modulating the function of TNF-alpha for hair cycling and is also involved in tissue repair (PMID: 16702408).