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- KD/KO Validated
CoraLite® Plus 488-conjugated DEK Monoclonal antibody
DEK Monoclonal Antibody for
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
5E3A6
验证数据展示
For other applications, we recommend the unconjugated version of this antibody, 66194-1-Ig
产品信息
CL488-66194 targets DEK in applications and shows reactivity with human samples.
| Tested Applications | Application Description |
| Tested Reactivity | human |
| Immunogen | DEK fusion protein Ag8225 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | DEK oncogene |
| Synonyms | D6S231E, 5E3A6 |
| Calculated Molecular Weight | 43 kDa |
| GenBank Accession Number | BC035259 |
| Gene Symbol | DEK |
| Gene ID (NCBI) | 7913 |
| RRID | AB_2919297 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P35659 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Dek oncogene(DEK) is first recognized in a fusion with CAN nucleoporin protein, and it's a also autoantigen in patients with pquciarticular onset juvenile rheumatoid arthritis. As a site-specific binding protein, DEK may involve in transcriptional regulation and signal transdcution. Analysis by agarose gel celctrophoresis, DEK showed to reduce the efficiency with which chromation is replicated. It's one of the first components of the splicing complex, which remains associate with spliced exons dependent on prior splicing of pre-mRNA.
