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验证数据展示

  • IF Staining of human ovary tumor using CL488-60047

    IF Staining of human ovary tumor using CL488-60047

    Immunofluorescent analysis of (4% PFA) fixed human ovary tumor tissue using CoraLite® Plus 488 EMILIN1 antibody (CL488-60047, Clone: 2A5C8 ) at dilution of 1:200.

  • IF Staining of human ovary tumor using CL488-60047

    IF Staining of human ovary tumor using CL488-60047

    Immunofluorescent analysis of (4% PFA) fixed human ovary tumor tissue using CoraLite® Plus 488 EMILIN1 antibody (CL488-60047, Clone: 2A5C8 ) at dilution of 1:200.

CoraLite® Plus 488-conjugated EMILIN1 Monoclonal antibody

EMILIN1 Monoclonal Antibody for IF-P
Cat No. CL488-60047

产品说明书

CloneNo. 2A5C8

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

IF-P

别名

DKFZp586M121, EMI, EMILIN, EMILIN 1, EMILIN1, gp115

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -

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经过测试的应用

Positive IF-P detected inhuman ovary tumor tissue
Planning an IHC experiment? We recommend our IHCeasy EMILIN1 Ready-To-Use IHC Kit. EMILIN1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 60047-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-60047 targets EMILIN1 in IF-P applications and shows reactivity with human samples.

经测试应用 IF-P Application Description
经测试反应性 human
免疫原 EMILIN1 fusion protein Ag1016 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 elastin microfibril interfacer 1
别名 DKFZp586M121, EMI, EMILIN, EMILIN 1, EMILIN1, gp115
计算分子量 107 kDa
观测分子量 120-130 kDa
GenBank蛋白编号BC007530
基因名称 EMILIN1
Gene ID (NCBI) 11117
RRIDAB_2919227
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ9Y6C2
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

EMILIN1, also named as EMILIN, EMILIN-1, gp115 and EMI, may be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. It has cell adhesive capacity. EMILIN1 is a negative regulator of the transforming growth factor-beta (TGF-beta) signaling, which is involved in blood pressure (BP) homeostasis (PMID:20186130). EMILIN1 may play a key role in hypertensive vascular remodeling. TGFβ proteins are the main regulators of blood vessel development and maintenance, and EMILIN1 inhibits TGFβ signaling by binding specifically to the proTGFβ precursor and preventing its maturation by furin convertases in the extracellular space (PMID:19922630).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 EMILIN1 antibody CL488-60047Download protocol
Standard Protocols
Click here to view our Standard Protocols