Lamin B2 Recombinant antibody
Lamin B2 Uni-rAbTM Recombinant Antibody for IF/ICC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
IF/ICC, ELISA
Conjugate
Unconjugated
CloneNo.
230184G4
验证数据展示
经过测试的应用
Positive IF/ICC detected in | HepG2 cells |
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:400-1:1600 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
82801-3-RR targets Lamin B2 in IF/ICC, ELISA applications and shows reactivity with human samples.
Tested Applications | IF/ICC, ELISA Application Description |
Tested Reactivity | human |
Immunogen | Lamin B2 fusion protein Ag1335 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | lamin B2 |
Synonyms | LMNB2, LMN2, Lamin-B2, LAMB2, 230184G4 |
Calculated Molecular Weight | 68 kDa |
GenBank Accession Number | BC006551 |
Gene Symbol | Lamin B2 |
Gene ID (NCBI) | 84823 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q03252 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Lamins are nuclear membrane structural components that are important in structural integrity of the nucleus and may also interact with chromatin (PMID: 33033404). Research studies show that lamin B2 knockout mice exhibit neuronal developmental defects and that both proteins are essential for typical brain development (PMID: 20145110). Mutations in Lamin B2 can result in a susceptibility to developing acquired partial lipodystrophy, a rare disorder characterized by the progressive loss of subcutaneous fat in a bilaterally symmetrical fashion (PMID: 16826530).
实验方案
Product Specific Protocols | |
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IF protocol for Lamin B2 antibody 82801-3-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |