验证数据展示
产品信息
82944-1-PBS targets MTF2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | MTF2 fusion protein Ag9384 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | metal response element binding transcription factor 2 |
Synonyms | MTF 2, Metal-response element-binding transcription factor 2, Metal-response element DNA-binding protein M96, M96, hPCl2 |
Calculated Molecular Weight | 536 aa, 61 kDa |
Observed Molecular Weight | 55 kDa, 60 kDa, 75 kDa |
GenBank Accession Number | BC010013 |
Gene Symbol | MTF2 |
Gene ID (NCBI) | 22823 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9Y483 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MTF2, also named as Metal-response element-binding transcription factor 2, is a 593 amino acid protein. It exists several isoforms and the range of the molecular weight of isoforms are about 55-60 kDa and 29 kDa. MTF2 contains 2 PHD-type zinc fingers and belongs to the Polycomblike family. MTF2 acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, leading to enhance PRC2 H3K27me3 methylation activity and regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation.