• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

P2RX6 Recombinant antibody, PBS Only

P2RX6 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241620B10

Cat no : 84458-4-PBS

Print datasheet

Synonyms

P2XM, P2X6, P2X purinoceptor 6, P2RXL1, ATP receptor

验证数据展示

  • WB analysis of mouse skeletal muscle using 84458-4-RR (same clone as 84458-4-PBS)

    WB analysis of mouse skeletal muscle using 84458-4-RR (same clone as 84458-4-PBS)

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 84458-4-RR (P2RX6 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84458-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84458-4-RR

    Affinity and Kinetic Characterization of 84458-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84458-4-RR against Human P2RX6 were performed. The affinity constant is below 1 pM.

产品信息

84458-4-PBS targets P2RX6 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen P2RX6 fusion protein Ag12331 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name purinergic receptor P2X, ligand-gated ion channel, 6
Synonyms P2XM, P2X6, P2X purinoceptor 6, P2RXL1, ATP receptor
Calculated Molecular Weight 431 aa, 48 kDa
Observed Molecular Weight 45 kDa
GenBank Accession NumberBC033488
Gene Symbol P2RX6
Gene ID (NCBI) 9127
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO15547
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The P2 receptors have two subfamilies in mammalian cells, P2X and P2Y. P2X family of ligand-gated ion channel receptors have seven members, P2RX1-7, which all constitute non-selective cation channels proposed to be functional under a homo- or heterotrimeric association. P2RX6 is predominantly expressed in skeletal muscle, and regulated by p53. It's reported that ATP might increase renal cell carcinoma cells migration and invasion through P2RX6.(PMID: 31159832, PMID:9242461)