验证数据展示
产品信息
67440-1-PBS targets PPM1D in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat, Pig samples.
经测试应用 | WB, IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human, Mouse, Rat, Pig |
免疫原 | PPM1D fusion protein Ag24761 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | protein phosphatase 1D magnesium-dependent, delta isoform |
别名 | PP2C DELTA, PPM1D, Protein phosphatase 1D, WIP1 |
观测分子量 | 67 kDa, 47 kDa |
GenBank蛋白编号 | BC060877 |
基因名称 | PPM1D |
Gene ID (NCBI) | 8493 |
RRID | AB_2882676 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | O15297 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PPM1D (also known as PP2Cd and WIP1) is a member of the PPM family, which is characterized by Mg2+/Mn2+-dependent activity and relative insensitivity to okadaic acid. The PPM1D gene is aberrantly amplified in a range of common cancers and encodes a protein phosphatase that is a potential therapeutic target (PMID: 17700519). This antibody can be detected two bands of 47 and 67 Kda.