验证数据展示
产品信息
68626-1-PBS targets PPM1F in WB, Indirect ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human |
免疫原 | PPM1F fusion protein Ag10316 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | protein phosphatase 1F (PP2C domain containing) |
别名 | CaM kinase phosphatase, CaMKPase, FEM 2, hFEM 2, KIAA0015, Partner of PIX 2, POPX2, PPM1F, Protein fem 2 homolog, Protein phosphatase 1F |
计算分子量 | 453 aa, 50 kDa |
观测分子量 | 50 kDa |
GenBank蛋白编号 | BC071989 |
基因名称 | PPM1F |
Gene ID (NCBI) | 9647 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P49593 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Mg2+/Mn2+-dependent protein phosphatase 1F (PPM1F) belongs to the PP2C family of Ser/Thr protein phosphatases and is the critical enzyme responsible for dephosphorylating the threonine motif. PPM1F is ubiquitous in various tissues and organs (PMID: 26498692). High expression of PPM1F was positively associated with poor survival and tumor recurrence in patients with cancers and PPM1F might be a potential biomarker in HCC patients (PMID: 30470261).