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CoraLite® Plus 488-conjugated Plasminogen Monoclonal antibody

Plasminogen Monoclonal Antibody for IF/ICC, IF-P

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

IF/ICC, IF-P

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

1F6A11

Cat no : CL488-66399

Print datasheet

Synonyms

PLG, Plasmin heavy chain A, short form, EC:3.4.21.7, Angiostatin, 1F6A11

验证数据展示

  • IF Staining of human liver cancer using CL488-66399

    IF Staining of human liver cancer using CL488-66399

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite® Plus 488 Plasminogen antibody (CL488-66399, Clone: 1F6A11 ) at dilution of 1:200.

  • IF Staining of human liver cancer using CL488-66399

    IF Staining of human liver cancer using CL488-66399

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite® Plus 488 Plasminogen antibody (CL488-66399, Clone: 1F6A11 ) at dilution of 1:200.

  • IF Staining of HepG2 using CL488-66399

    IF Staining of HepG2 using CL488-66399

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using CoraLite® Plus 488 Plasminogen antibody (CL488-66399, Clone: 1F6A11 ) at dilution of 1:200.

经过测试的应用

Positive IF-P detected inhuman liver cancer tissue
Positive IF/ICC detected inHepG2 cells
For other applications, we recommend the unconjugated version of this antibody, 66399-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)-PIF-P : 1:50-1:500
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-66399 targets Plasminogen in IF/ICC, IF-P applications and shows reactivity with human samples.

Tested Applications IF/ICC, IF-P Application Description
Tested Reactivity human
Immunogen Plasminogen fusion protein Ag9938 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name plasminogen
Synonyms PLG, Plasmin heavy chain A, short form, EC:3.4.21.7, Angiostatin, 1F6A11
Calculated Molecular Weight 810 aa, 91 kDa
Observed Molecular Weight 105 kDa
GenBank Accession NumberBC060513
Gene Symbol Plasminogen
Gene ID (NCBI) 5340
RRIDAB_2919320
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP00747
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Plasminogen is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Plasminogen is synthesized in the liver, and it circulates in the blood, with a half-life of 2.2 days. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products (FDP) and D-dimer; the conversion to active protease is mediated by tissue-type (tPA) and urokinase-type (uPA) plasminogen activators. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 Plasminogen antibody CL488-66399Download protocol
Standard Protocols
Click here to view our Standard Protocols