CoraLite®594-conjugated Plasminogen Monoclonal antibody
Plasminogen Monoclonal Antibody for IF-P
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
IF-P
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
1F6A11
验证数据展示
经过测试的应用
| Positive IF-P detected in | human liver cancer tissue |
For other applications, we recommend the unconjugated version of this antibody, 66399-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL594-66399 targets Plasminogen in IF-P applications and shows reactivity with human samples.
| Tested Applications | IF-P Application Description |
| Tested Reactivity | human |
| Immunogen | Plasminogen fusion protein Ag9938 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | plasminogen |
| Synonyms | Angiostatin, DKFZp779M0222, plasminogen, PLG |
| Calculated Molecular Weight | 810 aa, 91 kDa |
| Observed Molecular Weight | 105 kDa |
| GenBank Accession Number | BC060513 |
| Gene Symbol | Plasminogen |
| Gene ID (NCBI) | 5340 |
| RRID | AB_2919985 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P00747 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Plasminogen is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Plasminogen is synthesized in the liver, and it circulates in the blood, with a half-life of 2.2 days. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products (FDP) and D-dimer; the conversion to active protease is mediated by tissue-type (tPA) and urokinase-type (uPA) plasminogen activators. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL594 Plasminogen antibody CL594-66399 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |