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Anti-Human SIRP beta 1/CD172b Rabbit Recombinant Antibody, PBS Only

SIRP beta 1/CD172b Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

242115C10

Cat no : 98267-1-PBS

Print datasheet

Synonyms

SIRP BETA 1, SIRPB1, Signal-regulatory protein beta-1 isoform 3, Signal-regulatory protein beta-1, CD172b

验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98267-1-RR (same clone as 98267-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98267-1-RR (same clone as 98267-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human SIRP beta 1/CD172b Rabbit Recombinant Antibody (98267-1-RR, Clone: 242115C10) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98267-1-PBS in a different storage buffer formulation.

  • FC experiment of human peripheral blood leukocytes using 98267-1-RR (same clone as 98267-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98267-1-RR (same clone as 98267-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human SIRP beta 1/CD172b Rabbit Recombinant Antibody (98267-1-RR, Clone: 242115C10) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98267-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98267-1-RR

    Affinity and Kinetic Characterization of 98267-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98267-1-RR against Human SIRP beta 1/CD172b were performed. The affinity constant is 22.8 pM.

产品信息

98267-1-PBS targets SIRP beta 1/CD172b in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name signal-regulatory protein beta 1
Synonyms SIRP BETA 1, SIRPB1, Signal-regulatory protein beta-1 isoform 3, Signal-regulatory protein beta-1, CD172b
Calculated Molecular Weight43kDa
GenBank Accession NumberNM_006065.5
Gene Symbol SIRPB1
Gene ID (NCBI) 10326
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO00241-1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SIRP beta 1, also known as CD172b, is a member of the signal-regulatory-protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRP family members are cell surface signaling receptors differentially expressed in leukocytes and the central nervous system. SIRP beta 1 interacts with TYROBP/DAP12, a protein-bearing immunoreceptor tyrosine-based activation motif. SIRP beta 1 also participates in the recruitment of tyrosine kinase SYK.