验证数据展示
经过测试的应用
| Positive IF-P detected in | mouse brain tissue |
Planning an IHC experiment? We recommend our IHCeasy SYNPO Ready-To-Use IHC Kit. SYNPO primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 67339-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| IF | See 1 publications below |
产品信息
CL594-67339 targets SYNPO in IF-P applications and shows reactivity with Human, mouse, rat, pig samples.
| Tested Applications | IF-P Application Description |
| Cited Applications | IF |
| Tested Reactivity | Human, mouse, rat, pig |
| Immunogen | SYNPO fusion protein Ag15089 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | synaptopodin |
| Synonyms | KIAA1029, synaptopodin, SYNPO |
| Calculated Molecular Weight | 929 aa, 99 kDa |
| Observed Molecular Weight | 100-110 kDa |
| GenBank Accession Number | BC146665 |
| Gene Symbol | SYNPO |
| Gene ID (NCBI) | 11346 |
| RRID | AB_2920116 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | Q8N3V7 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Synaptopodin is a actin-associated protein expressed in mature dendritic spines and renal podocytes. Several isoforms of synaptopodin have been reported: the 100 kDa neural form and 110 kDa renal form. 44-45 kDa may represent the degradation product of synaptopodin. As a podocyte specific protein, synaptopodin expression level was decreased in kidney but increased in the urinary podocytes from patients with preeclampsia, indicating that synaptopodin is a useful marker for preeclampsia. (15841212, 10555072)
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL594 SYNPO antibody CL594-67339 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |