FITC Anti-Mouse TCR Beta (H57-597)

TCR Beta Monoclonal Antibody for FC
Cat No. FITC-65106

产品说明书

CloneNo. H57-597

宿主/亚型

Armenian Hamster / IgG

种属反应性

Mouse

应用

FC

T cell receptor beta chain, Tcrb, Tib

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inmouse splenocytes

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

FITC-65106 targets TCR Beta in FC applications and shows reactivity with Mouse samples.

经测试应用 FC Application Description
经测试反应性 Mouse
免疫原 Affinity purified TCR from mouse DO-11.10 cells 种属同源性预测
宿主/亚型 Armenian Hamster / IgG
抗体类别 Monoclonal
产品类型 Antibody
全称 T-cell receptor beta chain
别名 T cell receptor beta chain, Tcrb, Tib
基因名称 TCR beta
Gene ID (NCBI) 21577
RRIDAB_2883778
偶联类型 FITC Fluorescent Dye
最大激发/发射波长494 nm / 520 nm
形式 Liquid
纯化方式Affinity purification
储存缓冲液 PBS with 0.09% sodium azide and 0.1% gelatin , pH 7.2
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

T-cell receptor (TCR) consists of heterodimeric glycoproteins (TCR alpha/beta or gamma/delta) that demonstrate homology with immunoglobulins (PMID: 2144901). TCR beta is a member of the immunoglobulin superfamily and is expressed on alpha/beta TCR-bearing T cells and thymocytes. The TCR heterodimers are noncovalently associated with CD3. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta (PMID: 1826255). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).

实验方案

Product Specific Protocols
FC protocol for FITC TCR Beta antibody FITC-65106Download protocol
Standard Protocols
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