Atlantic Blue™ Anti-Mouse CD11c (N418)

CD11c Monoclonal Antibody for FC
Cat No. AB-65130

产品说明书

CloneNo. N418

宿主/亚型

Armenian Hamster / IgG

种属反应性

Mouse

应用

FC

AI449405, Cd11c, Cr4, integrin alpha X, Itgax

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inmouse splenocytes

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

AB-65130 targets CD11c in FC applications and shows reactivity with Mouse samples.

经测试应用 FC Application Description
经测试反应性 Mouse
免疫原 Mouse spleen dendritic cells 种属同源性预测
宿主/亚型 Armenian Hamster / IgG
抗体类别 Monoclonal
产品类型 Antibody
全称 integrin alpha X
别名 AI449405, Cd11c, Cr4, integrin alpha X, Itgax
GenBank蛋白编号BC167225
基因名称 CD11c
Gene ID (NCBI) 16411
RRIDAB_2935170
偶联类型 Atlantic Blue™ Fluorescent Dye
最大激发/发射波长404 nm / 458 nm
形式 Liquid
纯化方式Affinity purification
UNIPROT IDQ9QXH4
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).

实验方案

Product Specific Protocols
FC protocol for Atlantic Blue™ CD11c antibody AB-65130Download protocol
Standard Protocols
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