CoraLite® Plus 750 Anti-Mouse CD11c (N418)

CD11c Monoclonal Antibody for FC
Cat No. CL750-65130

产品说明书

CloneNo. N418

宿主/亚型

Armenian Hamster / IgG

种属反应性

Mouse

应用

FC

AI449405, Cd11c, Cr4, integrin alpha X, Itgax, N418

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inmouse splenocytes
For other applications, we recommend the unconjugated version of this antibody, 65130-1-Ig

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL750-65130 targets CD11c in FC applications and shows reactivity with Mouse samples.

经测试应用 FC Application Description
经测试反应性 Mouse
免疫原 Mouse spleen dendritic cells 种属同源性预测
宿主/亚型 Armenian Hamster / IgG
抗体类别 Monoclonal
产品类型 Antibody
全称 integrin alpha X
别名 AI449405, Cd11c, Cr4, integrin alpha X, Itgax, N418
GenBank蛋白编号BC167225
基因名称 CD11c
Gene ID (NCBI) 16411
RRIDAB_2935100
偶联类型 CoraLite® Plus 750 Fluorescent Dye
最大激发/发射波长755 nm / 780 nm
形式 Liquid
纯化方式Affinity purification
UNIPROT IDQ9QXH4
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).

实验方案

Product Specific Protocols
FC protocol for CL Plus 750 CD11c antibody CL750-65130Download protocol
Standard Protocols
Click here to view our Standard Protocols
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