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IHCeasy PBXIP1 Ready-To-Use IHC Kit

PBXIP1 Ready-to-use reagent kit for IHC.

Reactivity

Human, Mouse, Rat

Sample Type

FFPE tissue

Cat No : KHC1866

Synonyms

HPIP, PBXIP1

Validation Data Gallery

  • Immunohistochemical analysis of paraffin-embedded human malignant melanoma tissue slide using KHC1866 (PBXIP1 IHC Kit).

    Immunohistochemical analysis of paraffin-embedded human malignant melanoma tissue slide using KHC1866 (PBXIP1 IHC Kit).

  • Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using KHC1866 (PBXIP1 IHC Kit).

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using KHC1866 (PBXIP1 IHC Kit).

  • Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using KHC1866 (PBXIP1 IHC Kit).

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using KHC1866 (PBXIP1 IHC Kit).

  • Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue slide using KHC1866 (PBXIP1 IHC Kit).

    Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue slide using KHC1866 (PBXIP1 IHC Kit).

  • Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using KHC1866 (PBXIP1 IHC Kit).

    Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using KHC1866 (PBXIP1 IHC Kit).

  • Immunohistochemical analysis of paraffin-embedded rat small intestine tissue slide using KHC1866 (PBXIP1 IHC Kit).

    Immunohistochemical analysis of paraffin-embedded rat small intestine tissue slide using KHC1866 (PBXIP1 IHC Kit).

  • Components in IHCeasy ready-to-use IHC kit.

Product Information

KHC1866 is a ready-to-use IHC kit for staining of PBXIP1. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.

Product name IHCeasy PBXIP1 Ready-To-Use IHC Kit
Sample type FFPE tissue
Assay type Immunohistochemistry
Primary antibody type Rabbit Polyclonal
Secondary antibody type Polymer-HRP-Goat anti-Rabbit
Reactivity Human, Mouse, Rat

Kit components

ComponentSizeConcentration
Antigen Retrieval Buffer100 mL50×
Washing Buffer100 mL ×220×
Blocking Buffer5 mLRTU
Primary Antibody5 mLRTU
Secondary Antibody5 mLRTU
Chromogen Component A0.2 mLRTU
Chromogen Component B4 mLRTU
Signal Enhancer5 mLRTU
Counter Staining Reagent5 mLRTU
Mounting Media5 mLRTU
Datasheet1 Copy
Manual1 Copy

Background Information

PBXIP1 (pre-B-cell leukemia transcription factor-interacting protein 1), also known as HPIP (hematopoietic PBX-interacting protein), is a regulator of pre-B-cell leukemia transcription factors (BPXs) function. PBXIP1 is a nucleo-cytoplasmic shuttling protein, mainly localized in the cytosol and in small amounts in the nucleus. It interacts with PBX1 as well as PBX2 and PBX3. PBXIP1 inhibits the ability of PBX-HOX heterodimers to bind to target sequences and strongly inhibits the transactivation activity of E2A-PBX. PBXIP1 is also reported to be a microtubule-binding protein, which regulates estrogen receptor functions and plays a role in cancer development and progression.

Properties

Storage Instructions All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.
Synonyms HPIP, PBXIP1