验证数据展示
经过测试的应用
| Positive FC (Intra) detected in | LPS and Brefeldin A treated RAW 264.7 cells |
For other applications, we recommend the unconjugated version of this antibody, 98028-1-PBS
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL750-98028 targets MCP-1/CCL2 in FC (Intra) applications and shows reactivity with mouse samples.
| 经测试应用 | FC (Intra) Application Description |
| 经测试反应性 | mouse |
| 免疫原 | Fusion Protein 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | chemokine (C-C motif) ligand 2 |
| 别名 | Ccl2, MCP1, MCP-1, chemokine (C C motif) ligand 2, CCL-2 |
| GenBank蛋白编号 | NM-011333 |
| 基因名称 | MCP-1/CCL2 |
| Gene ID (NCBI) | 20296 |
| RRID | AB_3673790 |
| 偶联类型 | CoraLite® Plus 750 Fluorescent Dye |
| 最大激发/发射波长 | 755 nm / 780 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P10148 |
| 储存缓冲液 | PBS with 0.09% sodium azide. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Monocyte chemotactic protein 1 (MCP-1; also known as CCL2), is chemotactic for monocyte/macrophage, B-cell, and T-lymphocyte, and belongs to the CC subfamily of chemokines. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis.
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CL Plus 750 MCP-1/CCL2 antibody CL750-98028 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |